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Ehlers-Danlos Syndrome (EDS)

At Medserena we specialise in imaging for patients suffering from EDS, and as far as we are aware we are the only MRI Centre in the UK to do so. Upright MRI is able to provide a much more thorough examination of such patients due to it’s dynamic element, which is missing from “conventional” MRI where patients would typically be examined in a “passive” supine position only.

Our routine scan of the cervical spine is made sitting upright with the neck in the normal position, then flexed and then extended to give a dynamic study.

The cranio-cervical junction is also scanned sitting to allow full assessment of the, atlanto-axial joint (C1-C2), foramen magnum and cerebellar tonsils under the effects of gravity. As well as being performed sitting normally, further images are made with the head turned first to the right and then to the left giving a rotational dynamic study to assess for any instability or dislocation due to the presence of lax ligaments, not infrequently seen in persons with EDS.

In addition to these routine views a dynamic study of Cerebro-spinal fluid can also be made if required (CSF Flow studies)

Ehlers-Danlos Syndrome, often referred to as “EDS” is a collection of heritable connective tissue disorders. Either directly or indirectly, Ehlers-Danlos Syndrome is known or thought to alter the biology of collagen in the body (the most abundant protein), which can lead to multi-systemic symptoms. There are physical characteristics that are common to all types of Ehlers-Danlos Syndrome, including hypermobile joints (joints that move in greater amounts than expected) More information may be found at the Ehhers-Danlos Society Website:

 

 

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Clinical Applications

The Upright Positional MRI System offers the unique possibility of scanning patients in an upright or weight-bearing position.

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